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[5] Beyond sodium-channel antagonism, systemic lidocaine exhibits anti-inflammatory and antihyperalgesic properties attributed to inhibition of G-protein-coupled receptors, modulation of NMDA-mediated excitatory transmission, suppression of neutrophil priming, and attenuation of central glial activation

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[DOI] [PMC free article] [PubMed] [Google Scholar] 14.Hu J., Li S., Yu X., Dai L